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Intraoperative floppy iris syndrome (IFIS) is characterized by miosis, iris billowing, and prolapse in patients undergoing cataract surgery who have taken or currently take alpha-1-blockers.

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Peak urinary flow rate was increased statistically significantly from baseline to last assessment (Week 12) versus placebo in trials 1 and 2 (Table 5 and Figures 5, 6, and 7).

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The proportion of subjects who permanently discontinued treatment due to adverse reactions was less than 1%.

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The trial was sponsored by the National Institute of Diabetes and Digestive and Kidney Diseases, and Sanofi-Aventis provided the study drug and placebo at no cost.

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It is not intended as medical advice for individual conditions or treatment.

PAH refers to a narrowing of the vessels that carry blood between the lungs and heart; this narrowing increases blood pressure in the lungs and makes the heart work harder.

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